Learn from National Research Experts
We are shaping the next generation of leaders in medical research. Each year, we accept new students to perform their graduate research at Sanford Research through programs at the University of South Dakota and South Dakota State University.
Graduate students at Sanford Research learn all the skills necessary for a successful career in science and research, like developing scientific techniques, completing a thesis project and engaging daily with national research leaders. Watch the video below to hear from past students as they share their experiences:
Academic and research benefits
- Train with national research leaders with expertise in vast disciplines including biochemistry, cellular biology, developmental biology, neuroscience, genetics and more
- Complete three laboratory rotations during your first year before selecting a thesis advisor
- Complete elective courses on-site at Sanford Research
- Explore a variety of science careers through career development workshops; past topics have included biotech, pharmaceutical industry, undergraduate teaching, clinical laboratory directing, science policy and technology transfer
- Engage in K-12 outreach activities through Sanford PROMISE
- Host and learn from prominent guest speakers; past speakers have included Nobel laureates and Howard Hughes Medical Institute (HHMI) investigators
State-of-the-Art Science
Contribute to cutting-edge research using advanced technologies, such as super-resolution imaging on our Nikon CSU-W1 SoRa Spinning Disk Microscope (Histology & Imaging Core) or single-cell transcriptomics using our 10X Genomics Chromium X and Visium CytAssist systems (Functional Genomics & Bioinformatics Core). From CRISPR/Cas9 gene editing to generating 3D tumor models, Sanford Research labs are performing innovative research to address current questions in biomedical science.
Our Program Mentors
Location benefits
As a Sanford Research graduate student, you’ll get to live in Sioux Falls, SD – a city that is small enough to nurture Midwest values, but big enough to offer an abundance of dining, shopping and entertainment options. With sporting events, theater, concerts and a vibrant night life, there’s something for everyone. This “big small town” also is within driving distance of USD and SDSU.
How to apply
If you are interested in doing your graduate research in a Sanford Research lab, please apply to one of our affiliated programs. Links to the program websites, which provide details about the application process and program requirements, are listed below. Please indicate your interest in Sanford Research labs in your personal statement.
For questions about our graduate student opportunities, please email or call (605) 312-6590.
Graduate Opportunities
Biomedical and Translational Sciences Program (PhD)
You will learn in the classroom and laboratory – participating in laboratory investigations, developing original research, pursuing an interdisciplinary graduate education and more. With the Biomedical and Translational Sciences Program, you will work alongside our researchers as you further our understanding of human disease and translate that knowledge into novel approaches for diagnosis, treatment and therapeutics.
Physician Scientist Program (MD/PhD)
Collaboration between researchers and doctors has led to the most extraordinary advancements in medicine, and the Physician Scientist Program allows graduate students to gain experience as both. By blending the two disciplines of MD and PhD, you will perform translational research and develop a unique integration of skills that prepare you for a physician scientist career.
Biochemistry Program (PhD)
The skills needed to pursue a cutting-edge career await graduate students in the Biochemistry Program. Besides developing a solid biochemistry foundation, you will gain hands-on experience in a variety of learning formats to develop your laboratory skills. Through your research projects, you have the opportunity to understand human diseases and translate basic science findings into clinical treatments that impact patient care.
Student Success Stories
Meet Alicia Simmons
What leads a student from rural Mississippi to Sanford Research to pursue her PhD? That’s exactly the path that Alicia Simmons took to find her home away from home.
Meet Robin Fettig
When Robin Fettig enrolled at Concordia College in Moorhead, MN as a Biology and Psychology major, she did not envision pursuing a research career. A summer of research in the Sanford Program for Undergraduate Research (SPUR) changed that.
Meet Brook Busselman
Brook is a nontraditional student, researcher, husband and dad. He didn’t follow the conventional education timeline, but he’s now pursuing his true passion: biomedical research.
Meet Haydee Torres
Haydee Torres is a first-generation college graduate and the daughter of Cuban immigrants. Her work with Sanford Research helps her give back while working toward her professional goals.
Meet Hannah Wollenzien
Hannah has always wanted to pursue a career in research, and she feels more prepared than she could have imagined due to her Sanford Research mentors.
Meet Elle Anderson
Despite looking all across the country, Elle found the perfect graduate program for a career as a doctor and researcher right here close to home.
Meet Bethany Freel
A small town girl from Missouri toured Sanford Research with her undergraduate professor and found all she was looking for in a graduate program.
Where Are They Now Stories
Our Facility
Take a video tour of our research facility and collaborative open lab.
Sanford Health News
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Clinical trial gives cancer survivor a chance to help others
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Classes & Events
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Teen Science Café
Tue 01/13/26 5:30 PM - Tue 01/13/26 7:00 PM
Sanford Research Center -
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Teen Science Café
Tue 02/03/26 5:30 PM - Tue 02/03/26 7:00 PM