Careers

Sanford Research invites applications for full-time faculty at the rank of Assistant Scientist within Sanford Research in Sioux Falls, SD, with commensurate rank of Assistant Professor at the Sanford School of Medicine at the University of South Dakota. Sanford Research is the non-profit research branch under Sanford Health.

We seek outstanding scientists with research programs focused on investigating non-hematological pediatric cancers. Highly skilled candidates will explore genetic drivers, developmental mechanisms, and translational studies relevant to any non-hematological pediatric cancer, with a priority for candidates with research programs that focus on immunotherapies. Physician scientists are also encouraged to apply; however, candidates will be expected to dedicate a majority of their efforts guiding a basic or translational research laboratory. Investigators with established animal/cellular models of pediatric cancer are strongly encouraged to apply. Additionally, with our strong network of pediatric cancer oncologists and a strong network of clinical research coordinators, basic research programs that have the potential to drive future clinical trials will be preferred. Significant institutional support, including modern laboratory space and state-of-the-art facilities will be provided. A comprehensive benefits package will be tailored to the candidate’s qualifications. Successful candidates will join a collaborative team with a well-established infrastructure in pediatric and oncology research and faculty mentorship.

Qualifications
Applicants should hold a PhD, MD or MD/PhD degree and complement the existing strengths and interdisciplinary and collaborative nature of Sanford Research. Candidates will be expected to develop independent research programs and secure extramural funding.

Application
Sanford Health is an Equal Opportunity/Affirmative Action Employer. Applicants should submit a single PDF that includes: 1) detailed curriculum vitae, 2) description of research experience and future research plans with specific details on the relevance of their research to pediatric oncology, and 3) contact information for three letters of recommendation.

Submit materials via email to: researchrecruitment@sanfordhealth.org.

Sanford Research invites applications for full-time faculty at the rank of Assistant Scientist within Sanford Research in Sioux Falls, SD, with commensurate rank of Assistant Professor at the Sanford School of Medicine at the University of South Dakota. Sanford Research is the non-profit research branch under Sanford Health.

We seek outstanding scientists with research programs that span areas of biomedical research impacting rare diseases. This could include, but is not limited to, understanding the underlying cellular and molecular mechanisms of rare diseases, using animal models to understand disease progression and design therapeutic interventions, and developing new therapeutic approaches to treat rare diseases. Significant institutional support, including modern laboratory space and state-of-the-art facilities will be provided. A comprehensive benefits package will be tailored to the candidate’s qualifications. Successful candidates will join a collaborative team with a well-established infrastructure in rare disease research and faculty mentorship. In addition, successful candidates will have to opportunity to partner with the Coordination of Rare Diseases at Sanford (CoRDS) international rare disease patient registry whose mission is to facilitate the advancement of rare disease research.

Qualifications
Applicants should hold a PhD, MD or MD/PhD degree and complement the existing strengths and interdisciplinary and collaborative nature of Sanford Research. Physician Scientists are encouraged to apply. Candidates will be expected to develop independent research programs and secure extramural funding.

Application
Sanford Health is an Equal Opportunity/Affirmative Action Employer. Applicants should submit a single PDF that includes: 1) detailed curriculum vitae, 2) description of research experience and future research plans with specific details on the relevance of their research to relevance of their research to rare diseases, and 3) contact information for three letters of recommendation. Submit materials via email to: ResearchRecruitment@SanfordHealth.org.

About Sanford Health
Sanford Health, one of the largest health systems in the United States, is dedicated to the integrated delivery of health care, genomic medicine, senior care and services, global clinics, research and affordable insurance. Headquartered in Sioux Falls, South Dakota, the organization includes 47 medical centers, 2,800 physicians, over 220,000 Sanford Health Plan members, more than 200 Good Samaritan Society senior care locations, and World Clinics in 8 countries. Over $1 billion in gifts from philanthropist Denny Sanford have transformed how Sanford Health improves the human condition.

Postdoctoral Fellow/Staff Scientist – Savinov Lab
A position at the level of Postdoctoral Fellow or Staff Scientist is available in the lab of Dr. Alexei Savinov for a motivated and ambitious candidate with a strong background in Immunology and Molecular biology. Projects in the lab are focused on identifying cellular and molecular mechanisms leading to type 1 diabetes that are suitable for intervention, developing corresponding therapeutic approaches, and rigorous preclinical testing of these approaches.

Qualifications
Doctoral degree in molecular or cell biology, immunology, cancer biology, or a related field is required. Previous documented research experience with molecular cloning and Flow Cytometry is essential. A strong publication record along with advanced experience with primary cell culture, immunological techniques (such as ELISA, ELISPOT, Luminex, or manipulations of immune cells), and/or multi-color flow cytometry, is preferred. Familiarity with generating/characterizing mouse models, retroviral transduction, and immunofluorescent microscopy is highly desirable.

Application
Please send a CV, a cover letter and a list of three references to alexei.savinov@sanfordhealth.org with the subject line “Postdoctoral Fellow - Savinov Lab”.

Learn more about the Savinov Lab.

Faculty Position in Type 1 Diabetes Clinical Research, Sanford Research
Sanford Research invites applications for full-time faculty at any rank to support ongoing and future clinical trials in Type 1 Diabetes at Sanford Research in Sioux Falls, SD.  Sanford Research is the non-profit research organization under Sanford Health. Faculty include outstanding NIH-funded laboratory and clinically based investigators providing a stimulating environment and infrastructure with focused mentorship to facilitate the development of clinician scientists.  

At the inception of Sanford Research, type 1 diabetes was selected as the signature research focus, the Sanford Project. A central effort of this program is the Sanford PLEDGE program offering screening for type 1 diabetes genetic risk and autoantibodies to every child across the Sanford footprint. This relies on the innovative approach of automating recruitment and integrating study procedures into routine pediatric care. Children found to be at increased risk of type 1 diabetes are offered ongoing monitoring to detect progression in time to prevent ketoacidosis and to offer participation in relevant intervention trials. The Sanford Project also conducts a variety of type 1 diabetes intervention trials, including a mix of investigator-initiated, TrialNet, Immune Tolerance Network, and commercial studies that span from early stage to established clinical type 1 diabetes.

Responsibilities
Sanford Research includes basic and clinical investigators, clinical research coordinators, and dedicated regulatory staff working to impact type 1 diabetes care through investigations. Highly qualified candidates will be expected to participate in the conduct of current clinical research efforts and to implement additional trials. Ongoing clinical practice is expected, but the majority of effort will be dedicated to clinical research efforts.  

Qualifications
We are seeking a physician colleague holding a US license with an interest in pursuing an academic career in type 1 diabetes trials to join our team in a collaborative and supportive environment. Pediatric endocrine and clinical trial experience are preferred but not required. Early career investigators are encouraged to apply.  

Compensation
A comprehensive benefits package will be tailored to the candidate’s qualifications. Primary appointment and employment will be through Sanford Research, with appointment at a commensurate rank at the Sanford School of Medicine at the University of South Dakota. 

Application
Sanford Health is an Equal Opportunity/Affirmative Action Employer. Applicants should submit a single PDF that includes:

1. Detailed curriculum vitae
2. 2escription of research experience and future research plans
3. Three letters of recommendation.

Submit materials via email to researchrecruitment@sanfordhealth.org.

Postdoctoral position is available in the laboratory of Prof. Pilar de la Puente, Sanford Research, Sioux Falls to study dynamics of dysregulation of the extracellular matrix (ECM) composition in cancer. Dr. de la Puente lab’s mission is focused on the engineering of translational and physiologically relevant preclinical cancer models to advance cancer research. (https://delapuentelab.com/). The de la Puente Lab develops translational and physiologically relevant preclinical cancer models as tools to recapitulate tumor behavior ex vivo (“out of the living”) with an emphasis in cellular crosstalk, extracellular matrix remodeling, and spatial gradients.

We focus on elucidating mechanisms driving chemoresistance and immune evasion in cancer and further developing novel treatment strategies to mitigate their occurrence. Our long-term goal is to accelerate and directly translate our significant insights to aid patients suffering from cancer.

Qualifications
Interested candidate is expected to have recently obtained a PhD in Biomedical Engineering, Biology or similar discipline and be a first author on at least 1-2 publications in Cancer, cell-ECM mechanotransduction, and/or biomedical engineering applications.

The main job duty is to perform research to understand the role of tumor extracellular matrix remodeling in cancer chemoresistance and to identify novel therapeutic targets by using patient-derived 3D cultures (Funding already secured). The translational research project leverages multi-disciplinary approach in cancer biology, bio-orthogonal metabolic labeling, biomedical engineering/tissue engineering, mechanotransduction signaling, OMICs, and high-throughput in vitro patient-derived models to probe complex biological processes and to pursue new therapeutic opportunities for cancer.

Experience in 3D tissue cultures, confocal imaging and/or cancer biology is preferred. Excellent oral and written communication skills in English are required. Our laboratory is an inclusive and supportive environment, and we strongly encourage motivated individuals from historically excluded groups in science to apply.

Application
Please submit cover letter, CV, and contact information for 2-3 references combined into one PDF file by e-mail to: pilar.puente@sanfordhealth.org.