Tao Lab

Graduate Student Mentor
COBRE Project Leader

Primary Research Focus

The Tao Lab focuses on understanding the basic mechanisms underlying pathophysiological osteoblast function to effectively treat skeletal diseases like inborn osteosclerosis and osteosarcoma as well as to guide therapies like bone regeneration.

Skeletal NOTCH proteins regulate embryogenesis and play a critical role in osteoblast function and in skeletal development and homeostasis. Pathological notch signaling has emerged as a critical disease-mechanism for skeletal diseases.

The lab’s main goal is to dissect molecular mechanisms underlying NOTCH-related skeletal diseases, particularly within the setting of pathological osteoblast functions.

Dr. Tao’s research may provide novel mechanistic insights into the pathogenesis of skeletal diseases, explore regulatory and biochemical mechanisms in molecular detail in vivo, and open new opportunities for effective treatments of the diseases.

About the Tao Lab

Lab Projects and News

Meet the Tao Team