Histology and Imaging Core

Histology and Imaging Expertise

The Histology and Imaging Core is a centralized resource of expertise, equipment and technical capabilities. We support histological examination of tissues and cells, and provide access to advanced microscopy-based techniques and analysis for complete end-to-end analysis of biological samples (tissues to images/data).

The Histology and Imaging Core is supported by the Center for Cancer Biology Research CoBRE (NIGMS CoBRE P20GM103548).

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Services we provide:

  • Histology services for fresh, fixed or frozen tissue samples
    • Processing
    • Embedding
    • Sectioning frozen or embedded tissue 
    • Staining techniques o Hematoxylin/Eosin (H&E) staining
    • Immunohistochemistry (including antibody optimization)
    • Special stains
  • Light microscopy services (conventional and confocal)
    • Training on various imaging techniques and analysis
    • Assistance in acquiring live and fixed cell images
    • Technical assistance when using specialized imaging procedures (FRET, TIRF, etc.)
    • Automated whole slide/section imaging (brightfield/fluorescence)
  • Consultation on imaging projects
  • Troubleshooting imaging issues


  • Leica ASP300 Tissue Processor
  • Sakura Tissue-Tek III Embedder
  • Ventana Benchmark XT Tissue Stainer
  • Nikon A1R Confocal Microscope
  • Nikon A1 (with TIRF) Confocal Microscope
  • Olympus FV-1000 Confocal Microscope
  • Nikon Ni-E microscope (x2)
  • Olympus BX-51 microscope
  • Olympus IX-71 microscope
  • Nikon SMZ-1000 Stereomicroscope
  • StereoInvestigator System


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Madeo, M, Colbert, PL, Vermeer, DW, Lucido, CT, Cain, JT, Vichaya, EG, Grossberg, AJ, Muirhead, D, Rickel AP, Hong, Z, Zhao, J, Weimer, JM, Spanos, WC, Lee, JH, Dantzer, R, and Vermeer, PD. Cancer exosomes induce tumor innervation. Nature Communication. (2018).

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