De la Puente Lab

Graduate Student Mentor
COBRE Project Leader

Primary Research Focus

The de la Puente lab is focused on the role of tumor microenvironment (TME) in cancer progression, drug resistance and cancer immunology.

The TME is highly complex including stromal, immune, and endothelial cells, signaling molecules, oxygen tension, and the extracellular matrix. Classical two-dimensional (2D) cultures fail to provide an adequate model for the complexities of human tumors.

Our lab is developing personalized 3D models of the tumor microenvironment in order to more accurately mimic cell-cell and cell-matrix interactions.

Our lab currently focuses on developing three-dimensional models of solid tumors for personalized medicine. Through these culture models, we hope to gain a deeper understanding of the role of the tumor microenvironment and their accessory cells during cancer progression, drug resistance and cancer immunology for each individual patient.

About the de la Puente Lab

Lab Projects and News

Meet the de la Puente Lab Team