Explore Scientific Research Careers
Sanford Research offers the Sanford Program for Undergraduate Research (SPUR), which provides opportunities for undergraduate students interested in research careers to participate in research.
This dynamic summer program allows you to apply your classroom knowledge by working in a laboratory under the supervision of a principal investigator and interacting with research teams that include graduate students and postdoctoral fellows.
In addition to obtaining research experience in state-of-the-art facilities, you will attend weekly career and professional development workshops, as well as build your presentation and communication skills through scientific presentations. You will also benefit from the collegial and interactive research environment and enjoy the social community in Sioux Falls, a small city with an abundance of dining, shopping, sporting events and entertainment.
Summer Program Tracks
REU Site in Cellular and Molecular Biology: This National Science Foundation (NSF)-funded opportunity provides research experience in basic cellular and molecular biology. Students perform cutting-edge research in diverse areas, such as signal transduction, intracellular trafficking, cell proliferation and differentiation, organelle function and development.
Pediatric Biomedical Research Program: This National Institutes of Health (NIH) R25-funded opportunity provides research experience in biomedical areas directly and broadly related to pediatric health and disease. Projects range from basic studies of underlying disease mechanisms to translational research aimed at developing novel disease therapies.
Summer Program Details
- The SPUR program schedule is 10 weeks from June 6 through August 12, 2022. You must commit to working the entire ten weeks and participate in all program workshops.
- You will work under the direct supervision of a Sanford Research mentor as part of the mentor’s research team.
- You will prepare and present a short project proposal at the beginning of the program and a poster describing your research results in a symposium at the conclusion of the program.
- You will attend an introductory laboratory methods boot camp and weekly workshops geared toward career preparation and professional development, including topics such as ethics in research, science career opportunities and applying to graduate school.
- You will have the opportunity to attend regular research seminars and participate in a weekly GRE preparation course.
- You will engage in outreach activities to bring science to the local community.
- We organize social activities to enable casual interaction with other participants and mentors.
- We provide an educational stipend of $5,750 to each student.
- You can live free-of-charge on the Augustana University campus in Sioux Falls, South Dakota.
Any college student majoring in the life sciences, social sciences or other STEM fields is eligible to apply for the SPUR program. You should be in your freshman, sophomore or junior year at the time of application and should be interested in exploring careers in research and graduate school opportunities.
You are encouraged to apply if you attend an institution that does not have substantial research opportunities or are underrepresented in the biological sciences. This includes underrepresented minorities, first-generation college students, individuals from lower-income backgrounds or rural communities, students with disabilities and veterans or members of the Armed Services.
How to Apply
Please click on the link below to complete the common application for the SPUR program. In addition to the online application, all applicants must request the following to complete their application:
- An official or unofficial transcript from each college the applicant has attended or taken college-level courses.
- Two letters of recommendation, at least one of which must be from a college professor. Letters of recommendation sent via email must be sent from the author's email.
An application will not be considered complete until the application, letters of recommendation and transcript(s) have been received. Transcripts and letters of recommendation can be emailed or mailed to:
Attn: Tamara Ledeboer, Route 5031
2301 East 60th Street North
Sioux Falls, SD 57104
The application deadline is Monday, January 31st. All materials must be received by the deadline. Late applications will not be considered.Program Application: Applications will be available October 25, 2021.
Student Success Stories
Cancer Biology & Immunotherapies
Pilar De La Puente, PhD
Pilar De La Puente is an assistant scientist in the Cancer Biology and Immunotherapies Group at Sanford Research. She received her BSc in biology and master’s in animal medicine and surgery with a focus on biomedical engineering (BME) from University of Leon (Spain). During her PhD, she received a fellowship to perform research at the University of Salamanca and Tissue Bank San Francisco Clinic Foundation in Spain with a focus on tissue engineering. After being awarded her PhD, she continued her postdoctoral training in cancer biology at Washington University in Saint Louis School of Medicine in the laboratory of Dr. Azab, developing tissue-engineered cancer pre-clinical models and investigating localized drug delivery systems for hematological malignancies including multiple myeloma, lymphoma and breast cancer. In June 2018, she joined Sanford Research. Her lab’s interests are focused on the role of tumor microenvironment (TME) in cancer progression, drug resistance and cancer immunology.
Keith Miskimins, PhD
Dr. Keith Miskimins is a scientist in the Cancer Biology and Immunotherapies group at Sanford Research. He is the PI on the NIH funded Cancer Biology Research Center of Biomedical Research Excellence. His research focus is the protein inhibitor of cell cycle progression that is commonly down-regulated in cancer cells. He holds a bachelor’s degree in zoology from the University of Wyoming, and earned his master’s degree in genetics and doctoral degree in cell and developmental biology from the University of Arizona. He also completed post-doctoral training in cell and developmental biology at the University of Arizona and biology at Yale University.
Steven Powell, MD
Steven Powell, MD, is a practicing medical oncologist and a physician scientist. His laboratory focuses on integrating novel immunotherapies into the management of head and neck cancer and concurrently developing predictive biomarkers. His primary goal is to comprehend how to best incorporate immunotherapy into the management of locally advanced and metastatic head and neck cancer.
Dr. Powell’s research has led to novel strategies to use immune checkpoint inhibitors in combination with chemotherapy and radiation to augment anti-tumor response. Additionally, his work has evaluated biomarkers of immune response. As a clinician, Dr. Powell seeks to bring what he finds in the lab to clinical trials, to directly impact patient care.
Chad Spanos, MD
Dr. Chad Spanos is an assistant scientist in the Cancer Biology and Immunotherapies Group at Sanford Research. He is also a head and neck surgeon at Sanford Ear, Nose and Throat Clinic and an assistant professor in the department of surgery at the University of South Dakota Sanford School of Medicine. His lab focuses on head and neck squamous cell cancer (HNSCC), specifically the incidence of a subset of HNSCC caused by the human papillomavirus, which is increasing rapidly. Dr. Spanos holds an MD from the University of Louisville Medical School, completed his residency in otolaryngology at the University of Iowa and served as a fellow at the University of South Florida.
Jianning Tao, PhD
Dr. Jianning Tao received his doctor of philosophy degree in biochemistry/developmental biology at the University of Tennessee Health Science Center in Memphis, TN, where he performed his dissertation work in the laboratory of Dr. John Cunningham at St. Jude Children’s Research Hospital. Subsequently, Dr. Tao performed postgraduate work in the laboratory of Dr. Brendan Lee and Dr. Dennis Roop at the Baylor College of Medicine in Houston, TX, in the departments of Molecular and Human Genetics and Molecular and Cell Biology, first as a postdoctoral fellow and then as an assistant professor. Currently he is a principal investigator and primary faculty member in Cancer Biology and Immunotherapies group at Sanford Research and an assistant professor at the Department of Pediatrics of the University of South Dakota School of Medicine.
Paola Vermeer, PhD
Dr. Paola Vermeer obtained her BA in biology from Brandeis University in Waltham, MA, in 1991, her PhD from Columbia University in New York City, NY, in 1998. She did a post-doctoral research fellowship at the Howard Hughes Medical Institute at the University of Iowa with Dr. Michael J. Welsh. She stayed on as a research scientist with Dr. Welsh and then Dr. Joseph Zaber until 2008 when she joined the Cancer Biology Research Center at Sanford Research, Sioux Falls, SD.
Cellular Therapies & Stem Cell Biology
Kevin Francis, PhD
Dr. Kevin Francis received his bachelor’s in biology from Marshall University, a master’s in anatomy from the University of Georgia and a doctorate in neuropathology from the Medical University of South Carolina in 2009. He completed his postdoctoral training at the Eunice Kennedy Shriver National Institute of Child Health and Human Development in the laboratories of Heiner Westphal and Denny Porter (NICHD). There, Dr. Francis developed induced pluripotent stem cell (iPSC) models of pediatric disorders of cholesterol synthesis and metabolism, including Smith-Lemli-Opitz Syndrome and Niemann-Pick disease, Type C1. In 2015, Dr. Francis joined the faculty of Sanford Research, where he continues to use patient-derived iPSCs as a tool for modeling rare pediatric disease and identification of targets for therapeutic intervention.
Alexei Savinov, MD, PhD
Dr. Alexei Savinov has been studying diabetes pathogenesis for more than 20 years. He is passionate about understanding how different checkpoints in adaptive immunity are affected during development of autoimmunity. After graduating from The 1st Leningrad Medical Academy (Leningrad, USSR) with an MD and specialization in surgery, he obtained a PhD in biochemistry and cell biology at the Institute for Experimental Medicine, Academy of Medical Sciences of USSR (Leningrad, USSR). Dr. Savinov completed two postdoctoral fellowships: first, in the Department of Pharmacology and Experimental Therapeutics at the University of Maryland, School of Medicine (Baltimore, MD) and second, in The Jackson Laboratory (Bar Harbor, ME). Later, he worked as a staff scientist at the Sanford-Burnham Medical Research Institute (La Jolla, CA) before joining Sanford Research as an assistant scientist.
Indra Chandrasekar, PhD
Indra Chandrasekar obtained her master’s degree from Birla Institute of Technology and Science, Pilani, India. Her passion for cell biology took her to cytoskeletal research pioneer Dr. Brigitte M. Jockusch’s Lab in Germany, where she received training in basic cell biology concepts and techniques. After receiving her PhD (Dr.rer.nat) degree from Technical University of Braunschweig in Germany, she moved to the U.S. Dr. Chandrasekar performed a short postdoctoral fellowship in the laboratory of renowned actin biologist Dr. John Cooper at Washington University School of Medicine in St. Louis to continue her training in cytoskeletal research. After a baby break, she joined the lab of Dr. Paul Bridgman, an expert cellular neurobiologist and EM specialist at Washington University, where she received training in neuronal cytoskeleton, mouse models and advanced microscopy techniques. She is currently an assistant scientist in the Enabling Technologies Group at Sanford Research, establishing her lab that will study membrane trafficking in vertebrate systems.
Kyle Roux, PhD
Kyle Roux received his BS in Biological anthropology/human biology at Emory University in 1998, and his PhD in neuroscience at the University of Florida College of Medicine in 2004. Subsequently, Kyle performed postgraduate work at the University of Florida College of Medicine in the Department of Anatomy and Cell Biology, first as a postdoctoral associate and then as a research assistant professor. Currently he is a faculty member in the Sanford Enabling Technologies Group and principal investigator in the Roux Lab.
Environmental Influences on Health & Disease
Michelle Baack, MD
Dr. Michelle Baack obtained her BS in pharmacy from South Dakota State University (SDSU) in 1991, her MD from the University of South Dakota-School of Medicine (USD) in 1995, and her pediatric residency training from the University of Nebraska Medical Center-Creighton Joint Pediatric Residency Program in 1999. She practiced as a general pediatrician in rural South Dakota for 10 years and later returned to academics to obtain her fellowship in neonatal and perinatal medicine at the University of Iowa in 2008. She completed her neonatology training in 2011 and joined Sanford as a physician – scientist. She is board certified in pediatrics and neonatal and perinatal medicine. She is a clinical neonatologist at Sanford Children’s Hospital; an assistant professor through the Sanford School of Medicine of the University of South Dakota; a principal investigator at the Sanford School of Medicine of the University of South Dakota; and a principal investigator in Sanford Research’s Environmental Influences on Health and Disease Group in Sioux Falls, SD.
Genetics & Genomics
Randy Faustino, PhD
Randy Faustino made the move to South Dakota and joined Sanford Research in 2016, where his lab is focused on exploring the role of nuclear biology in pluripotency and cardiac development. Before joining Sanford, Dr. Faustino earned his BSc (microbiology) from the University of Manitoba in Winnipeg, Canada. He stayed on at the U of M, and began graduate studies under the mentorship of Dr. Grant Pierce, where he studied the role of nuclear transport in smooth muscle cell biology and its role in atherosclerosis. After being awarded his PhD in physiology, he continued his postdoctoral training in cardiac development, transcriptome analysis and stem cell biology at Mayo Clinic in the laboratory of Dr. Andre Terzic. His lab’s interests are focused on the potential epigenomic functions of nucleoporins in controlling stem cell and cardiac biology, as well as characterizing the systems biology impacts of nucleoporin mutations in development and disease.
Mike Kareta, PhD
Mike Kareta is an associate scientist in the Genetics and Genomics Group at Sanford Research. He earned his bachelor of science in molecular and cellular biology at Texas A&M University where in the lab of Dr. Flora Katz he investigated the role of Abelson in the development of retinal neurons is Drosophila. He earned his PhD in the lab of Dr. Frédéric Chédin at the University of California, Davis where he investigated the biochemical mechanisms which underlie DNA Methyltransferase (DNMT) function. He then completed his postdoctoral studies at Stanford university in the labs of Drs. Julien Sage and Marius Wernig. It was at Stanford that he utilized iPS reprogramming to investigate Rb function and identified Sox2 as a key player in tumor formation. In September 2016 he joined Sanford Research.
Pediatrics & Rare Diseases
Jill Weimer, PhD
Jill is an associate scientist in the pediatrics and Rare Diseases Group and assistant professor in the Department of Pediatrics at the Sanford School of Medicine at USD. Before joining the Pediatrics and Rare Disease team at Sanford, Dr. Weimer completed a BS and PhD in neuroscience at the University of Rochester and a postdoctoral fellowship at the University of North Carolina, Chapel Hill in the Neuroscience Center.
Lance Lee, PhD
Principal Investigator Lance Lee obtained his bachelor of science in biochemistry from Boston College in 1995, his MS in genetics from the University of Connecticut in 1997, and his Ph.D. in cell and developmental biology from Stony Brook University in 2004. He then did a postdoctoral fellowship at Children’s Hospital Boston/Harvard Medical School, where he studied genetic causes of primary ciliary dyskinesia in mouse models. He is currently a faculty member in the Pediatric and Rare Diseases Group at Sanford Research, where he oversees the research projects in the Lee Lab with ongoing interests in cilia biology and primary ciliary dyskinesia genetics.
Dr. Pilaz received his PhD in Lyon, France, and then moved to the United States where he trained as a postdoctoral fellow at Johns Hopkins University School of Medicine and Duke University. He studies the cellular and molecular mechanisms that regulate the development of the cerebral cortex and how their disruption can lead to neurodevelopmental diseases such as autism and microcephaly.
Kamesh Surendran, PhD
Kamesh is an associate scientist in the Pediatric and Rare Diseases Group at Sanford Research, and assistant professor in the Department of Pediatrics at the Sanford School of Medicine, University of South Dakota. He has been involved in studying the Wnt, TGF/BMP, and Notch signaling pathways, three evolutionarily conserved signaling pathways, in various aspects of kidney development and disease during his doctoral thesis and post-doctoral work at Washington University School of Medicine, St. Louis. His current research interests are: (i) to understand the cellular and molecular abnormalities that result in childhood cystic kidney diseases and (ii) to determine the molecular regulators of cell fate patterning in the collecting ducts of the kidney.
Student Success Stories
SPUR Intern in 2017, 2018
College: St. John’s University, St. Joseph, MN
Current Location: PhD Candidate, University of Iowa
“SPUR is great if you want to get a true research experience. Principal investigators will allow you to work on a real project and make that project your own. The people and culture are inviting. The PI and others are approachable and easy to talk to.”
Annika van Oosbree
SPUR Intern in 2017
College: Northern State University, Aberdeen, SD
Current Location: MD and PhD Candidate, University of South Dakota and Sanford Research
“My research experience confirmed my desire to pursue an MD and PhD. It also provided me with invaluable connections to continue molding myself into a competitive candidate to be admitted into an MD and PhD program. SPUR was the most pivotal point during my undergraduate education in helping me to fully realize my career goals.”
SPUR Intern in 2016
College: Central Methodist University, Fayette, MO
Current Location: PhD Candidate, University of South Dakota and Sanford Research
“Sanford Research is truly a gem that few people know about. SPUR itself has wonderful leadership that is quick to answer any questions or solve any issues that may arise. The experience that I had as an intern prepared me for graduate school in a very short amount of time.”
SPUR Intern in 2014-2015
College: Augustana University, Sioux Falls, SD
Current Location: MD and PhD Candidate, University of South Dakota and Sanford Research
“I gained a strong appreciation of and love for basic scientific research. I also gained a host of technical, writing and thinking skills. Most people at Sanford Research are incredibly friendly and willing to provide assistance or advice. In modern research where collaboration and teamwork are essential for success, I'd say this is one of Sanford Research's biggest strengths.”
SPUR Intern in 2014
College: Arizona State University, Tempe, AZ
Current Location: MD Candidate, Johns Hopkins University School of Medicine
“I chose Sanford Research because of SPUR's dedication to diversity in research and medicine. Funny enough, I applied to SPUR on a whim and thought I'd be extremely lucky if I got accepted. It was the only program I applied to. A better question might be why Sanford Research chose me? I'm glad they did. At the time, I was a college sophomore with no research experience and nothing extraordinary going for me. SPUR is special because, despite that, they saw potential and decided to help me develop that potential.”
Congratulations to Our 2019 Interns
For 10 weeks, these undergraduates got hands-on research experience with professionals in the field. Apply for the SPUR program to conduct research while still an undergraduate. Sanford Research also offers some research opportunities during the academic year. Contact us if you have questions about SPUR, its application process or research programs during the school year.
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