Kyle Roux BioID Vice President Sanford Research Nuclear Envelope, Laminopathies
 
Tiles spelling out science

Meet The Scientists Kyle Roux

Dr. Kyle Roux is not only a leading scientist at Sanford Research, but is also the innovator of BioID, a revolutionary lab tool used to isolate and identify specific protein interactions. From Emory University and the University of Florida, Dr. Roux brought his expertise in BioID and the nuclear envelope to Sanford Research in 2011. From there, he built his lab on the fundamentals of compassion and joint success; “...if the other people in your department aren’t doing well, then you’re not going to do well” (Roux). These principles are what make Dr. Roux a highly respected leader in the scientific community at Sanford Research.

Written by Reid Hammerquist, 2026 PROMISE Scholar

After growing up in Florida, Dr. Kyle Roux moved to Atlanta to attend Emory University. He originally wanted to get a degree on a pre-medical or pre-veterinarian school track but later decided to major in Biological Anthropology. Once he graduated from Emory, he moved to the University of Florida for graduate school under their interdisciplinary program. There, he worked on a protein cell biology project while gaining his PhD in neuroscience. He stayed as a junior faculty member and research assistant professor while working in the department of anatomy and cell biology. After a few years, Dr. Roux inherited the lab project of his post-doctoral mentor, who left the university. This is where he created the idea for BioID while developing his passion for research on the nuclear envelope. In 2011, Dr. Roux left the University of Florida and accepted a research position at Sanford Research. Here, he finally published his work on BioID and received a large R01 grant from the NIH to continue developing his project on the nuclear envelope. At the time, Sanford Research was a new institution, and he was able to establish himself as one of the lead researchers while gradually moving into different leadership positions. Currently, he serves as a scientist in the Center for Genetics and Rare Diseases Research and the Vice President of Biomedical Research.

Dr. Roux’s primary focus is researching the biology of the nuclear envelope, the membrane barrier that holds together the contents of the cell’s nucleus inside the cytoplasm. Using the application of BioID, his lab is working on characterizing the processes and consequences of nuclear envelope rupture. On top of BioID, his lab uses many other techniques, such as molecular cloning, live cell imaging, and cell line generation to study the ways that the cell senses and repairs the nuclear envelope rupture. He is also trying to understand the complex links between nuclear envelope ruptures and various diseases such as cardiomyopathy, muscular dystrophy, and numerous others.

Outside of his outstanding work at Sanford Research, Dr. Kyle Roux enjoys many different hobbies, such as cooking and gardening. He likes to take time during his weekends to make different meals for him and his family. When he’s not cooking, you can find Dr. Roux outside, working in his personal garden. On top of this, he has recently started brewing beer from home. He doesn’t consider himself a professional by any means, but he has a five-gallon conical brewer and uses various extract kits to create his homemade beer.

Education Pathway:

Bachelor of Science, Biological Anthropology and Human Biology: Emory University

PhD in Neuroscience: University of Florida College of Medicine

Post-Doctoral Training: University of Florida College of Medicine, department of Anatomy and Cell Biology