Arielle Deutsch, PhD
Dr. Arielle Deutsch’s lab primarily focuses on how advantaged and disadvantaged groups experience health disparities related to alcohol misuse and sexual health over age. She joined Sanford Research in 2017 and is an assistant scientist in the Population Health group. She is also an assistant professor in the department of pediatrics at the University of South Dakota Sanford School of Medicine. Dr. Deutsch earned her bachelor’s degree in psychology at SUNY Binghamton and her PhD in developmental psychology with a concentration in quantitative methods at the University of Nebraska. While pursuing her PhD, her work focused on developmental sexual health and wellbeing. At the University of Missouri, Dr. Deutsch completed a postdoctoral fellowship in alcohol and addictions. During this time, she received an F32 NIH grant to continue her training on developmental behavior genetic etiologies of alcohol use.
Arielle Selya, PhD
Dr. Arielle Selya’s lab explores the etiology of smoking and nicotine addiction among adolescents, specifically the role of early-emerging nicotine dependence and the hereditary and/or environmental mechanisms by which risk factors act to increase smoking behavior. She is most interested in studying the effects of maternal smoking and prenatal tobacco exposure on youth smoking behavior. With the rise of electronic cigarettes, she’s been studying their impact on conventional smoking behavior. Dr. Selya has a quantitative educational background and has researched extensively on substance use and addiction, particularly tobacco use and nicotine dependence in youth. In her work, she uses advanced quantitative methods to answer new questions about the causation factors of addiction. Her other Sanford projects include analyzing administrative health data to improve healthcare delivery.
Emily Griese, PhD
Dr. Emily Griese holds a PhD in psychological research from the University of Nebraska-Lincoln and completed her postdoctoral work in population health while at Sanford Research. Her current research focuses on exploring social determinants of health among several communities, particularly at-risk youth and rural populations. Dr. Griese is committed to translational research for health care delivery, working closely with Sanford Health to leverage integrated health care data that impacts patient care delivery.
Cancer Biology & Immunotherapies
Pilar De La Puente, PhD
Pilar De La Puente is an assistant scientist in the Cancer Biology and Immunotherapies Group at Sanford Research. She received her BSc in biology and master’s in animal medicine and surgery with a focus on biomedical engineering (BME) from University of Leon (Spain). During her PhD, she received a fellowship to perform research at the University of Salamanca and Tissue Bank San Francisco Clinic Foundation in Spain with a focus on tissue engineering. After being awarded her PhD, she continued her postdoctoral training in cancer biology at Washington University in Saint Louis School of Medicine in the laboratory of Dr. Azab, developing tissue-engineered cancer pre-clinical models and investigating localized drug delivery systems for hematological malignancies including multiple myeloma, lymphoma and breast cancer. In June 2018, she joined Sanford Research. Her lab’s interests are focused on the role of tumor microenvironment (TME) in cancer progression, drug resistance and cancer immunology.
Sam Milanovich, MD
Sam Milanovich received his BA in biology from Augustana College and his MD from the University of North Dakota School of Medicine. He completed residency in pediatrics at the Children’s Hospital of Pittsburgh of UPMC and went on to a clinical fellowship in pediatric hematology and oncology at the Children’s Hospital of Wisconsin in Milwaukee, WI. His post-graduate research fellowship training was in hematopoiesis and stem cell biology at the Blood Research Institute and Medical College of Wisconsin. Dr. Milanovich is currently an assistant scientist at the Cancer Biology and Immunotherapies Group, a pediatric hematologist/oncologist at Sanford Children’s Hospital and an assistant professor of pediatrics at the University of South Dakota Sanford School of Medicine.
Keith Miskimins, PhD
Dr. Keith Miskimins is a scientist in the Cancer Biology and Immunotherapies group at Sanford Research. He is the PI on the NIH funded Cancer Biology Research Center of Biomedical Research Excellence. His research focus is the protein inhibitor of cell cycle progression that is commonly down-regulated in cancer cells. He holds a bachelor’s degree in zoology from the University of Wyoming, and earned his master’s degree in genetics and doctoral degree in cell and developmental biology from the University of Arizona. He also completed post-doctoral training in cell and developmental biology at the University of Arizona and biology at Yale University.
Steven Powell, MD
Steven Powell, MD, is a practicing medical oncologist and a physician scientist. His laboratory focuses on integrating novel immunotherapies into the management of head and neck cancer and concurrently developing predictive biomarkers. His primary goal is to comprehend how to best incorporate immunotherapy into the management of locally advanced and metastatic head and neck cancer.
Dr. Powell’s research has led to novel strategies to use immune checkpoint inhibitors in combination with chemotherapy and radiation to augment anti-tumor response. Additionally, his work has evaluated biomarkers of immune response. As a clinician, Dr. Powell seeks to bring what he finds in the lab to clinical trials, to directly impact patient care.
Chad Spanos, MD
Dr. Chad Spanos is an assistant scientist in the Cancer Biology and Immunotherapies Group at Sanford Research. He is also a head and neck surgeon at Sanford Ear, Nose and Throat Clinic and an assistant professor in the department of surgery at the University of South Dakota Sanford School of Medicine. His lab focuses on head and neck squamous cell cancer (HNSCC), specifically the incidence of a subset of HNSCC caused by the human papillomavirus, which is increasing rapidly. Dr. Spanos holds an MD from the University of Louisville Medical School, completed his residency in otolaryngology at the University of Iowa and served as a fellow at the University of South Florida.
Jianning Tao, PhD
Dr. Jianning Tao received his doctor of philosophy degree in biochemistry/developmental biology at the University of Tennessee Health Science Center in Memphis, TN, where he performed his dissertation work in the laboratory of Dr. John Cunningham at St. Jude Children’s Research Hospital. Subsequently, Dr. Tao performed postgraduate work in the laboratory of Dr. Brendan Lee and Dr. Dennis Roop at the Baylor College of Medicine in Houston, TX, in the departments of Molecular and Human Genetics and Molecular and Cell Biology, first as a postdoctoral fellow and then as an assistant professor. Currently he is a principal investigator and primary faculty member in Cancer Biology and Immunotherapies group at Sanford Research and an assistant professor at the Department of Pediatrics of the University of South Dakota School of Medicine.
Paola Vermeer, PhD
Dr. Paola Vermeer obtained her BA in biology from Brandeis University in Waltham, MA, in 1991, her PhD from Columbia University in New York City, NY, in 1998. She did a post-doctoral research fellowship at the Howard Hughes Medical Institute at the University of Iowa with Dr. Michael J. Welsh. She stayed on as a research scientist with Dr. Welsh and then Dr. Joseph Zaber until 2008 when she joined the Cancer Biology Research Center at Sanford Research, Sioux Falls, SD.
Cellular Therapies & Stem Cell Biology
Kevin Francis, PhD
Dr. Kevin Francis received his bachelor’s in biology from Marshall University, a master’s in anatomy from the University of Georgia and a doctorate in neuropathology from the Medical University of South Carolina in 2009. He completed his postdoctoral training at the Eunice Kennedy Shriver National Institute of Child Health and Human Development in the laboratories of Heiner Westphal and Denny Porter (NICHD). There, Dr. Francis developed induced pluripotent stem cell (iPSC) models of pediatric disorders of cholesterol synthesis and metabolism, including Smith-Lemli-Opitz Syndrome and Niemann-Pick disease, Type C1. In 2015, Dr. Francis joined the faculty of Sanford Research, where he continues to use patient-derived iPSCs as a tool for modeling rare pediatric disease and identification of targets for therapeutic intervention.
Alexei Savinov, MD, PhD
Dr. Alexei Savinov has been studying diabetes pathogenesis for more than 20 years. He is passionate about understanding how different checkpoints in adaptive immunity are affected during development of autoimmunity. After graduating from The 1st Leningrad Medical Academy (Leningrad, USSR) with an MD and specialization in surgery, he obtained a PhD in biochemistry and cell biology at the Institute for Experimental Medicine, Academy of Medical Sciences of USSR (Leningrad, USSR). Dr. Savinov completed two postdoctoral fellowships: first, in the Department of Pharmacology and Experimental Therapeutics at the University of Maryland, School of Medicine (Baltimore, MD) and second, in The Jackson Laboratory (Bar Harbor, ME). Later, he worked as a staff scientist at the Sanford-Burnham Medical Research Institute (La Jolla, CA) before joining Sanford Research as an assistant scientist.
Indra Chandrasekar, PhD
Indra Chandrasekar obtained her master’s degree from Birla Institute of Technology and Science, Pilani, India. Her passion for cell biology took her to cytoskeletal research pioneer Dr. Brigitte M. Jockusch’s Lab in Germany, where she received training in basic cell biology concepts and techniques. After receiving her PhD (Dr.rer.nat) degree from Technical University of Braunschweig in Germany, she moved to the U.S. Dr. Chandrasekar performed a short postdoctoral fellowship in the laboratory of renowned actin biologist Dr. John Cooper at Washington University School of Medicine in St. Louis to continue her training in cytoskeletal research. After a baby break, she joined the lab of Dr. Paul Bridgman, an expert cellular neurobiologist and EM specialist at Washington University, where she received training in neuronal cytoskeleton, mouse models and advanced microscopy techniques. She is currently an assistant scientist in the Enabling Technologies Group at Sanford Research, establishing her lab that will study membrane trafficking in vertebrate systems.
Kyle Roux, PhD
Kyle Roux received his BS in Biological anthropology/human biology at Emory University in 1998, and his PhD in neuroscience at the University of Florida College of Medicine in 2004. Subsequently, Kyle performed postgraduate work at the University of Florida College of Medicine in the Department of Anatomy and Cell Biology, first as a postdoctoral associate and then as a research assistant professor. Currently he is a faculty member in the Sanford Enabling Technologies Group and principal investigator in the Roux Lab.
Environmental Influences on Health & Disease
Michelle Baack, MD
Dr. Michelle Baack obtained her BS in pharmacy from South Dakota State University (SDSU) in 1991, her MD from the University of South Dakota-School of Medicine (USD) in 1995, and her pediatric residency training from the University of Nebraska Medical Center-Creighton Joint Pediatric Residency Program in 1999. She practiced as a general pediatrician in rural South Dakota for 10 years and later returned to academics to obtain her fellowship in neonatal and perinatal medicine at the University of Iowa in 2008. She completed her neonatology training in 2011 and joined Sanford as a physician – scientist. She is board certified in pediatrics and neonatal and perinatal medicine. She is a clinical neonatologist at Sanford Children’s Hospital; an assistant professor through the Sanford School of Medicine of the University of South Dakota; a principal investigator at the Sanford School of Medicine of the University of South Dakota; and a principal investigator in Sanford Research’s Environmental Influences on Health and Disease Group in Sioux Falls, SD.
Peter Vitiello, PhD
Peter Vitiello has been researching molecular responses to oxidative stress for 15 years and is interested in understanding how atmospheric chemicals influence lung development and disease. After graduating from Lafayette College with a Bachelor of Science in biology, he obtained a PhD in toxicology in the Department of Environmental Medicine at the University of Rochester School of Medicine and Dentistry. Peter continued as a postdoctoral fellow in the Department of Pediatrics at the University of Rochester School of Medicine and Dentistry. Currently, he is an assistant scientist in the Environmental Influences on Health and Disease Group and assistant professor of pediatrics at the University of South Dakota Sanford School of Medicine.
Genetics & Genomics
Randy Faustino, PhD
Randy Faustino made the move to South Dakota and joined Sanford Research in 2016, where his lab is focused on exploring the role of nuclear biology in pluripotency and cardiac development. Before joining Sanford, Dr. Faustino earned his BSc (microbiology) from the University of Manitoba in Winnipeg, Canada. He stayed on at the U of M, and began graduate studies under the mentorship of Dr. Grant Pierce, where he studied the role of nuclear transport in smooth muscle cell biology and its role in atherosclerosis. After being awarded his PhD in physiology, he continued his postdoctoral training in cardiac development, transcriptome analysis and stem cell biology at Mayo Clinic in the laboratory of Dr. Andre Terzic. His lab’s interests are focused on the potential epigenomic functions of nucleoporins in controlling stem cell and cardiac biology, as well as characterizing the systems biology impacts of nucleoporin mutations in development and disease.
Mike Kareta, PhD
Mike Kareta is an associate scientist in the Genetics and Genomics Group at Sanford Research. He earned his bachelor of science in molecular and cellular biology at Texas A&M University where in the lab of Dr. Flora Katz he investigated the role of Abelson in the development of retinal neurons is Drosophila. He earned his PhD in the lab of Dr. Frédéric Chédin at the University of California, Davis where he investigated the biochemical mechanisms which underlie DNA Methyltransferase (DNMT) function. He then completed his postdoctoral studies at Stanford university in the labs of Drs. Julien Sage and Marius Wernig. It was at Stanford that he utilized iPS reprogramming to investigate Rb function and identified Sox2 as a key player in tumor formation. In September 2016 he joined Sanford Research.
Pediatrics & Rare Diseases
Jill Weimer, PhD
Jill is an associate scientist in the pediatrics and Rare Diseases Group and assistant professor in the Department of Pediatrics at the Sanford School of Medicine at USD. Before joining the Pediatrics and Rare Disease team at Sanford, Dr. Weimer completed a BS and PhD in neuroscience at the University of Rochester and a postdoctoral fellowship at the University of North Carolina, Chapel Hill in the Neuroscience Center.
Lance Lee, PhD
Principal Investigator Lance Lee obtained his bachelor of science in biochemistry from Boston College in 1995, his MS in genetics from the University of Connecticut in 1997, and his Ph.D. in cell and developmental biology from Stony Brook University in 2004. He then did a postdoctoral fellowship at Children’s Hospital Boston/Harvard Medical School, where he studied genetic causes of primary ciliary dyskinesia in mouse models. He is currently a faculty member in the Pediatric and Rare Diseases Group at Sanford Research, where he oversees the research projects in the Lee Lab with ongoing interests in cilia biology and primary ciliary dyskinesia genetics.
Kamesh Surendran, PhD
Kamesh is an associate scientist in the Pediatric and Rare Diseases Group at Sanford Research, and assistant professor in the Department of Pediatrics at the Sanford School of Medicine, University of South Dakota. He has been involved in studying the Wnt, TGF/BMP, and Notch signaling pathways, three evolutionarily conserved signaling pathways, in various aspects of kidney development and disease during his doctoral thesis and post-doctoral work at Washington University School of Medicine, St. Louis. His current research interests are: (i) to understand the cellular and molecular abnormalities that result in childhood cystic kidney diseases and (ii) to determine the molecular regulators of cell fate patterning in the collecting ducts of the kidney.
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